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ALS Treatment Considerations

No cure has yet been found for ALS. However, there are some treatments available to help relieve symptoms and improve the quality of life for people with ALS. There is also a FDA-approved therapy proven to extend survival of patients with ALS. Research is continuing to find the cause(s) of ALS, understand the mechanisms involved in disease progression, and develop other effective treatments.

Relief of Symptoms

Medication and assistive devices may be necessary to help relieve ALS-related symptoms, such as:

  • depression, anxiety, and insomnia
  • shortness of breath
  • excessive saliva or drooling
  • muscle spasms, stiffness
  • emotional lability
  • weight loss, malnutrition
  • constipation
  • urinary urgency or frequency

Speak to your healthcare provider about the treatments available to relieve these symptoms.

ALS Therapies

Rilutek

Rilutek has been proven to extend survival time to tracheostomy or death, and is the only medication currently approved by the U.S. Food and Drug Administration for the treatment of ALS.

Rilutek has been used by neurologists and other physicians to treat ALS patients for more than 10 years.

Additional Therapies

As ALS progresses and muscles weaken, patients may benefit from rehabilitation services to enhance independence and maintain safety, such as:

  • Physical therapy -to strengthen muscles, improve cardiovascular health, and fight fatigue.
  • Occupational therapy -to maintain performance of daily tasks.
  • Speech therapy -because ALS affects the muscles used to speak and swallow.
  • Assistive devices-such as braces, canes, walkers, wheelchairs and communication devices.
  • Nutritional support -advice on foods that are nutritious and easy to swallow; gastrostomy tube leadings.
  • Emotional support -utilizing medication and counseling if a patient becomes anxious or depressed.
  • Respiratory support -non invasive (BiPAP) or invasive (tracheostomy) mechanical ventilation.

Important Safety Information

  • You should not take Rilutek if you are allergic to any of its ingredients.
  • Call your doctor if you have a fever while taking Rilutek.
  • Rilutek may cause you to feel dizzy, light-headed, or sleepy. If you experience any of these, you should NOT drive a vehicle or use machinery.
  • If you miss or skip a dose of Rilutek, do not take any extra tablets to make up for those you missed, but take your prescribed dose at the next regularly scheduled time.
  • When taking Rilutek, avoid drinking excessive amounts of alcohol; alcohol may contribute to compromising liver function and may be associated with an increased risk of liver problems.
  • The most common side effects of Rilutek are weakness, nausea, lung function decrease*, a mild liver disorder that is typically temporary, runny nose and headache. If any side effects become troublesome, contact your doctor.
  • Be sure to tell your doctor and pharmacist about all other medicines you are taking, including nonprescription products and vitamins. If you have questions, please talk to your doctor.
* Not associated with a reduction in vital capacity
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US.RIL.07.07.001 Last Update: May 2007